In some managed Exchange 2007 and 2010 environments, the preferred Domain Controller used by Exchange servers is different from the Domain Controller used by the Active Directory connector. As a result, the Active Directory replication latency can introduce mailbox creation failure. To prevent mailbox creation failure, configure the Exchange Server so that it communicates directly with the Active Directory connector-preferred Domain Controller.
To resolve the issue, set the ADS_E2K_SEND_DC system environment variable on the IM_CCS computer to 1.
Note: By default the value of the ADS_E2K_SEND_DC system environment variable value is 0.
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