The MDB should not be removed except in extreme cases.
Before removing an MDB, make sure the data stored in the database is no longer needed and that all products that were accessing the database have been uninstalled or configured to work with another MDB. Once an MDB is removed the data is lost.
Note: You should make a backup of the MDB before removing it, especially if more than one product has shared it.
To remove a SQL Server Management Database
mdb.signature.txt
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