You can use multiple communication services and protocols on the same system. But you can use only one protocol - XCF, VTAM LU 6.2, or VTAM LU 0 - for communication between any two systems at any one time.
A Typical Implementation
The use of multiple communication services and protocols is illustrated below. The z/OS systems S01, S02, and S03 are in a sysplex, while z/OS system S04 is not. XCF is used for communication among S01, S02, and S03, while VTAM LU 0 is used for communication between S03 and S04.

The communication setup shown above allows the following communication between CA-L-Serv applications:
Note: A CA-L-Serv application running on S01 or S02 cannot communicate with a CA-L-Serv application running on S04. That is, S03 does not act as a gateway between S01/S02 and S04.
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